3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)- - Names and Identifiers
Name | 3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)-
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Synonyms | N-Boc-3-oxa-7-azabicyclo[3.3.1]nonan-9-ol 3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy... tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate(9-syn) (1R,5S,9r)-tert-butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate tert-butyl (1R,5S,9r)-9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate (9-Anti)-9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid 1,1-dimethylethyl ester 3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)- 3-OXA-7-AZABICYCLO[3.3.1]NONANE-7-CARBOXYLIC ACID, 9-HYDROXY-, 1,1-DIMETHYLETHYL ESTER, (9-ANTI)-
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CAS | 228270-33-5
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3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)- - Physico-chemical Properties
Molecular Formula | C12H21NO4
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Molar Mass | 243.29944 |
3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)- - Introduction
3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)-is a chemical compound, its structural formula is Boc-Oxanorbornene-Nine-Tert-butyl alcohol ester or Boc-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethyleyl ester, (9-anti)-.
General nature:
-Appearance: White to slightly yellow crystal/powder
-Solubility: Soluble in organic solvents such as acetonitrile, dimethylformamide and dichloromethane
Use:
- 3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)-is a commonly used protecting group compound and is widely used in organic synthesis. By means of this, compounds having active or reactive groups can be protected to prevent them from reacting unnecessarily during the synthesis.
-It can also be used as an intermediate for the synthesis of other compounds.
Method:
3-Oxa-7-azabicyclo[3.3.1] The preparation of nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)-usually involves the following steps:
1. React 3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid with 1,1-dimethylether alcohol to generate [3.3.1]nonane-7-carboxylic acid.
2. The above product is reacted with Boc2O or Boc2O · Ti(OTeF5)2 to generate 7-Boc-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid.
3. Finally, the above product is reacted with an activating agent (such as DCC or EDC) to form 7-Boc-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid tert-butyl ester.
Safety Information:
The safety information about 3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester, (9-anti)-requires careful operation in synthesis and use. Always follow proper laboratory procedures and use personal protective equipment during use. In addition, proper handling and disposal in accordance with chemical safety instructions and relevant local regulations.
Last Update:2024-04-09 21:54:55